The super-hot gut-activating supplement is here!
Developed from joint research with APt's patented platinum and academia
General sales have started from pre-sales to hair salons.
Available on Amazon.
Please search Mulberry Flora.

Slimming intestinal bacteria growth supplement

Increase slimming bacteria, a super-hot topic on the internet and TV.

APt has just patented it!

APt Co., Ltd. and Kurimura's next-generation, patented collaboration intestinal activity# supplement will be the first product of its kind in the world. Platinum nanocolloid developed by APt after years of research and evolution combines excellent properties that other nanocolloids do not have.

In particular, it has excellent adaptability in removing hydrogen peroxide and active oxygen in the large intestine, enabling the growth of Akkermansia muciniphila

#Our busy lives are disrupting our diets. A diet high in protein and fat can contribute to an increase in bad bacteria in the intestines. The most important thing is to be conscious of your daily diet for the sake of intestinal health. At the same time, it is to regulate the intestinal environment through a well-balanced diet and moderate exercise.

Description of our supplements by Mr. Okayama, President of APt Co., Ltd.

Greetings, this is Mr. Okayama from APT Co.Ltd.  Today, I would like to introduce to you Mulberry Flora, which specializes in providing a habitat environment for intestinal bacteria and food for them to use.

Mulberry Flora, which specializes in providing a habitat environment for intestinal bacteria and food for these bacteria to use. Before I start, do you know what the intestinal bacteria that live deep inside the large intestine live on?

Dietary fiber. The Ministry of Health, Labor and Welfare has announced that the recommended daily intake of dietary fiber is 21g for men and 18g or more for women.

Since we normally consume only about 14g, we are deficient by about 7g.

Especially important is dietary fiber. This is fermentable fiber. About half of Mulberry Flora is made up of fermentable fiber. We recommend that you take Mulberry Flora along with your daily diet. Mulberry Flora is a dietary supplement designed for intestinal bacteria.

Mulberry Flora supports the growth of intestinal bacteria in three ways.

First, the fiber in the mulberry leaf provides a home for good anaerobic bacteria in the stool. Second, the fermented guar gum decomposition products provide a ready-to-use food source. Third, and this is the most important part that no other company can copy, platinum nanocolloids absorb and decompose active oxygen and excess oxygen in the large intestine and convert them into water.

In particular, the reductive intestinal environment provided by platinum nanocolloids has three characteristics that other nutrients cannot provide.

First, platinum nanocolloids are antioxidants that are not absorbed and can reach the large intestine without fail. Second, because platinum nanocolloids are catalysts, they continue to work like enzymes.

Third, and this is a recently discovered fact, the latest generation 3D platinum nanocolloid, which has been uniquely engineered by our company, has been confirmed in clinical trials to increase Ackermansia muscinifera, the next generation of beneficial bacteria, commonly known as slimming bacteria, and a patent has been granted for this technology. 

Akkermansia muciniphila.

Akkermansia muciniphila  is an extremely selective eater that eats only mucins from the mucosa layer, and thus requires nutrients such as short-chain fatty acids produced by the surrounding intestinal bacteria and an extremely oxygen-unfriendly environment. Mulberry Flora's food design provides this environment and increases the number of beneficial bacteria in the colon, including Akkermansia muciniphila in the body. Recent medical research has shown that this growth stimulus is very beneficial to the health of the human body. The increase in Akkermansia muciniphila, which only feeds on mucins in the mucosal layer, causes a reaction that thickens the mucosa and increases the barrier of the intestine.

Hence, our patent title is "A composition for the growth of Akkermansia muciniphila, which increases the intestinal bacteria Akkermansia that strengthens the intestinal mucosal barrier and improves the intestinal environment.

Our latest generation 3D platinum nanocolloids have been engineered over many years to have an excellent ROS decomposition activity 30 times that of our conventional products. Moreover, they have a more homogeneous particle distribution between 1 and 2 nm than ever before. The smaller the particle size of the catalyst, the larger the surface area and the more efficient it is. However, in general, small particles are unstable and platinum, which has a much heavier specific gravity than water (21.45 times), will settle out in a few days. However, our unique equilibration technology makes it possible to provide extremely stable products.

With this design based on a large amount of evidence, we will be the first company to release a third-party product approved by APt. We hope you will try it out for yourself.

Minenobu Okayama, APt Co., Ltd.

Next Generation Beneficial Bacteria

Health Proposal with Akkermansia muciniphila Enhancement

What is Akkermansia muciniphila?

The mucosal surfaces of the digestive organs, such as the stomach and intestines, are covered with mucin, a viscous substance that protects them from bacterial invasion, etc. In 2004, *Muriel Derrien of the Netherlands isolated a bacterium from healthy human feces that can live on mucin as a single nutrient source. The bacteria was named Akkermansia muciniphila after the name of a renowned Dutch microbial ecologist (Antoon Akkermans) and its "mucin-loving" characteristics.

*Derrien M. et al. Int. J. Syst. Evol. Microbiol. 54(Pt 5), 1469-1476 (2004)

Akkermansia muciniphila is found in the feces of infants during the first months of life. By the age of six months, approximately 70% of infants are carriers of the organism, and by the age of one year, the rate reaches 90%, the same level as that of adults. Akkermansia muciniphila is carried by one in five adults and accounts for 1-4% of the total number of intestinal bacteria, placing it in the class of bacteria that inhabit the intestines.

Association with obesity and diabetes

It is believed that people with high body weight, body mass index (BMI), blood cholesterol, and fasting blood glucose levels have less Akkermansia muciniphila in their intestines than normal people. It has also been reported that when overweight or obese people follow a calorie-restricted diet, the improvement of insulin resistance is more hesitant in those who originally have more Akkermansia muciniphila in their intestines, suggesting a relationship with obesity and diabetes.

Akkermansia muciniphila is expected to be applied to diagnostic index of effectiveness of diet therapy and therapy for improvement of insulin resistance.

Beneficial bacteria found relatively recently

Akkermansia muciniphila is a Gram-negative, biased anaerobic bacterium belonging to the Phylum Verrucomicrobia, and was isolated from healthy human feces by Derrien et al. in 2004 and proposed as a new genus Akkermansia. The genus name is derived from Antoon Akkermans, a renowned Dutch microbiologist. It was named A. muciniphila (mucin-loving) because of its unique characteristic of using mucin (glycoprotein) secreted from intestinal cells as the sole source of carbon and nitrogen. Only two species of bacteria in the genus Akkermansia have been isolated and classified so far: A.

muciniphila and A. glycaniphila (isolated from the feces of a myrmecophagous snake). 

Beginning to be applied to supplements in Europe and the U.S.

We have confirmed that platinum nanocolloid intake promotes the growth of Akkermansia muciniphila.

It is reported that 79% of all women do not have this bacterium, but in this clinical trial, Akkermansia muciniphila, commonly known as the slimming bacterium, increased even in subjects below the detection limit

Many women who have trouble losing weight are

It is highly likely that they need to review their intestinal environment.

Slimming bacteria (Ackermansia muscinifera) can be increased by improving one's diet and taking effective supplements. 腸内の断面図

 内藤教授著書「腸内細菌叢」※154ページ

Nano Platinum Colloid of APt

Since the initial development of platinum, it has undergone numerous developmental improvements and is highly regarded overseas as a next-generation type of platinum and is expected to have a synergistic advantage when combined with antioxidant and high-end cosmetic ingredients in EU cosmetic development.
As for its use as a food additive, a new research and development has proved in a clinical test that "Ackermansia muscinifera bacteria (Ackermansia muscinifera) increase in those who do not have Ackermansia muscinifera by eating platinum by APt. Furthermore, the daily intake of platinum has been shown to increase the number of Akkermansia bacteria, resulting in the acquisition of our patent.
The presence or absence of Ackermansia, the amount of other beneficial bacteria, the stress environment, exercise, and diet are all factors that contribute to a person's inability to lose weight.

 The APT Mark of Approval is a mark of trust that indicates high quality
Ltd. is committed to manufacturing and selling products that faithfully reproduce the research and clinical trial data of APT Co.

Authorized by Apt Co., Ltd. Authorized Distributor 

Kurimura Co. , Ltd.

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